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Patients who had common side effects (%)

Most common side effects Januvia®
100 mg + metformin
Victoza® + metformin
Nausea 4.6% 23.9%
Headache 10.0% 10.3%
Diarrhea 4.6% 9.3%
Vomiting 4.1% 8.7%
Minor low blood sugar 5.0% 5.0%

Nausea is most common when first starting Victoza®, but decreases over time in most people.

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Patients who had common side effects (%)

Most common side effects Byetta® 10 mcg twice daily + metformin and/or sulfonylurea Victoza® 1.8 mg once daily + metformin and/or sulfonylurea
Nausea 28.0% 25.5%
Diarrhea 12.1% 12.3%
Headache 10.3% 8.9%
Dyspepsia 4.7% 8.9%
Vomiting 9.9% 6.0%
Constipation 2.6% 5.1%

Victoza® and other type 2 diabetes medicines

In medical studies that compared Victoza® with Januvia® (the leading branded pill) or Byetta®, more people with type 2 diabetes taking Victoza® reached their A1C goal of <7%. People taking Victoza® also saw better results in fasting blood sugar reduction and better or comparable weight loss.

Victoza® is not for weight loss, but it may help you lose some weight. In clinical studies ranging from 26 to 52 weeks in length, many people lost some weight. In our largest study, when Victoza® was added to metformin, people lost on average up to 6.2 pounds. While many people in clinical trials lost weight, some did gain weight.

In the study comparing Victoza® with Januvia®, more patients taking Victoza® experienced nausea as well as headache, diarrhea, and vomiting.

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