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Common side effects in patients (%)

Most common side effects Januvia®
100 mg + metformin
Victoza® + metformin
Nausea 4.6% 23.9%
Headache 10.0% 10.3%
Diarrhea 4.6% 9.3%
Vomiting 4.1% 8.7%
Minor low blood sugar 5.0% 5.0%

Nausea is most common when first starting Victoza®, but decreases over time in most people.

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Common side effects in patients (%)

Most common side effects Byetta® 10 mcg twice daily + metformin and/or sulfonylurea Victoza® 1.8 mg once daily + metformin and/or sulfonylurea
Nausea 28.0% 25.5%
Diarrhea 12.1% 12.3%
Headache 10.3% 8.9%
Dyspepsia 4.7% 8.9%
Vomiting 9.9% 6.0%
Constipation 2.6% 5.1%

Victoza® and other type 2 diabetes medications

In medical studies that compared Victoza® with Januvia® (the leading branded pill) or Byetta®, more people with type 2 diabetes taking Victoza® reached their A1C goal of <7%. People taking Victoza® also saw better results in fasting blood sugar reduction and better or comparable weight loss.

Victoza® is not for weight loss, but it may help you lose some weight. In clinical studies ranging from 26 to 52 weeks in length, many people lost some weight. In a large study, when Victoza® was added to metformin, people lost on average up to 6.2 pounds. While many people in clinical trials lost weight, some did gain weight.

In the study comparing Victoza® with Januvia®, more patients taking Victoza® experienced nausea as well as headache, diarrhea, and vomiting.

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