Taking care of your Victoza^® Pen

Caring for the Pen

• After removing the needle, put the cap on your Victoza^® Pen and store your Victoza^® Pen without the needle attached.
• Do not try to refill your Victoza^® Pen—it is prefilled and is disposable.
• Do not try to repair your Pen or pull it apart.
• Keep your Victoza^® Pen away from dust, dirt, and liquids.
• If cleaning is needed, wipe the outside of the Pen with a clean, damp cloth.

Storing the Pen

Before use:

• Store your new, unused Victoza^® Pen in the refrigerator at 36°F to 46°F (2°C to 8°C).
• If Victoza^® is stored outside of refrigeration (by mistake) prior to first use, it should be used or thrown away within 30 days.
• Do not freeze Victoza^® or use Victoza^® if it has been frozen. Do not store Victoza^® near the refrigerator cooling element.

Pen in use:

• Store your Victoza^® Pen for 30 days at 59°F to 86°F (15°C to 30°C), or until expiration in a refrigerator at 36°F to 46°F (2°C to 8°C).
• When carrying the Pen away from home, store the Pen at a temperature between 59°F and 86°F (15°C and 30°C).
• If Victoza^® has been exposed to temperatures above 86°F (30°C), it should be thrown away.
• Protect your Victoza^® Pen from excessive heat and sunlight.
• Keep the cap on when your Victoza^® Pen is not in use.
• Use a Victoza^® Pen for only 30 days. Throw away a used Victoza^® Pen after 30 days.

Important Information

• Do not share your Victoza^® Pen with anyone else.
• Keep your Victoza^® Pen out of the reach of children.
• Always use a new needle for each injection.
• If you drop your Victoza^® Pen, repeat “First-Time Use for Each New Pen” (steps A through D in the IFU).
• Be careful not to bend or damage the needle.
• Do not use the cartridge scale to measure how much Victoza^® to inject.
• Remove the needle from the Victoza^® Pen after each injection. This helps to ensure sterility and prevent leakage of Victoza^®, and will help to make sure you inject the right dose of Victoza^® for future injections.
• Be careful when handling used needles to avoid needle sticks.
• You can use your Victoza^® Pen for up to 30 days after you use it for the first time.

Pen Safety

Do not store the Victoza^® Pen with the needle attached. Always safely remove and safely throw away the needle after each injection. This may help prevent contamination, infection, and leakage. It also helps to make sure that you get the correct dose of Victoza^®.

Keep your Victoza^® Pen, pen needles, and all medications out of the reach of children.

For more information about how to dispose of used pen needles and used Victoza^® Pens, see the Instructions for Use.

Indications and Usage

Victoza^® is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes when used along with diet and exercise.

Victoza^® is not recommended as the first medication to treat diabetes. Victoza^® is not a substitute for insulin and has not been studied in combination with prandial (meal-time) insulin. Victoza^® is not for people with type 1 diabetes or people with diabetic ketoacidosis. It is not known if Victoza^® is safe and effective in children. Victoza^® is not recommended for use in children.

Important Safety Information

In animal studies, Victoza^® caused thyroid tumors—including thyroid cancer—in some rats and mice. It is not known whether Victoza^® causes thyroid tumors or a type of thyroid cancer called medullary thyroid cancer (MTC) in people, which may be fatal if not detected and treated early. Do not use Victoza^® if you or any of your family members have a history of MTC or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). While taking Victoza^®, tell your doctor if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer.

Do not use Victoza^® if you are allergic to liraglutide or any of the ingredients in Victoza^®. Serious allergic reactions can happen with Victoza^®. If symptoms of serious allergic reactions occur, stop taking Victoza^® and seek medical attention. Inflammation of the pancreas (pancreatitis) may be severe and lead to death. Before taking Victoza^®, tell your doctor if you have had pancreatitis, gallstones, a history of alcoholism, or high blood triglyceride levels since these medical conditions make you more likely to get pancreatitis.

Stop taking Victoza^® and call your doctor right away if you have pain in your stomach area that is severe and will not go away, occurs with or without vomiting, or is felt going from your stomach area through to your back. These may be symptoms of pancreatitis.

Before using Victoza^®, tell your doctor about all the medicines you take, especially sulfonylurea medicines or insulin, as taking them with Victoza^® may affect how each medicine works. If you use Victoza^® with insulin, you may give both injections in the same body area (for example, your stomach area), but not right next to each other.

Also tell your doctor if you have severe stomach problems such as slowed emptying of your stomach (gastroparesis) or problems with digesting food; have or have had kidney or liver problems; have any other medical conditions; or are pregnant or plan to become pregnant. Tell your doctor if you are breastfeeding or plan to breastfeed. It is unknown if Victoza^® will harm your unborn baby or if Victoza^® passes into your breast milk.

Your risk for getting hypoglycemia, or low blood sugar, is higher if you take Victoza^® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. The dose of your sulfonylurea medicine or insulin may need to be lowered while taking Victoza^®.

Victoza^® may cause nausea, vomiting, or diarrhea leading to dehydration, which may cause kidney failure. This can happen in people who have never had kidney problems before. Drinking plenty of fluids may reduce your chance of dehydration.

The most common side effects with Victoza^® include headache, nausea, and diarrhea. Nausea is most common when first starting Victoza^®, but decreases over time in most people. Immune system related reactions, including hives, were more common in people treated with Victoza^® compared to people treated with other diabetes drugs in medical studies.

Please click here for Prescribing Information and Medication Guide.

Novo Nordisk provides patient assistance for those who qualify.
Please call 1-866-310-7549 to learn more about Novo Nordisk assistance programs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch , or call 1-800-FDA-1088.