How Victoza® Works

Victoza® works in 3 ways to lower blood sugar

  1. Victoza® slows food leaving your stomach
  1. Victoza® helps prevent your liver from making too much sugar
  1. Victoza® helps the pancreas produce more insulin when your blood sugar levels are high
  1. Victoza® slows food leaving your stomach
  1. Victoza® helps prevent your liver from making too much sugar
  1. Victoza® helps the pancreas produce more insulin when your blood sugar levels are high

Victoza® works in 3 ways like the hormone GLP-1 (7-37)a to help control blood sugar. GLP-1 is normally released from your small intestine when you eat. This slows down the process of food leaving your stomach, which helps control your blood sugar levels after meals. GLP-1 also keeps your liver from making too much sugar and helps your pancreas produce more insulin.

Victoza® helps your pancreas produce more insulin by helping important cells work the way they should. These cells are called beta cells, and they help control blood sugar by making and releasing insulin.

aGLP-1 (7-37) represents <20% of the total circulating GLP-1 produced by your body.

Victoza® is not insulin

Victoza® is not insulin. But it can be taken with long-acting insulin. When using Victoza® with insulin, take them as separate injections. You may give both injections in the same body area (for example, your stomach area), but you should not give the injections right next to each other. Never mix insulin and Victoza® together.

Victoza® may also be taken alone or in combination with one or more common oral type 2 diabetes medicines. These include biguanides (such as metformin), sulfonylureas (SUs), and thiazolidinediones (TZDs).

While not a weight-loss product, Victoza® may help you lose some weight

Medical studies showed that most people taking Victoza® lost some weight. The American Diabetes Association recommends weight loss as an important goal for overweight people with type 2 diabetes.

Save on Victoza®. See how you may be able to save money on your Victoza® prescription.

Indications and Usage

What is Victoza®?

Victoza® is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes, and should be used along with diet and exercise.

  • Victoza® is not recommended as the first choice of medicine for treating diabetes.
  • It is not known if Victoza® can be used in people who have had pancreatitis.
  • Victoza® is not a substitute for insulin and is not for use in people with type 1 diabetes or people with diabetic ketoacidosis.
  • It is not known if Victoza® can be used with mealtime insulin.
  • It is not known if Victoza® is safe and effective for use in children.

Important Safety Information

What is the most important information I should know about Victoza®?

Victoza® may cause serious side effects, including:

  • Possible thyroid tumors, including cancer. Tell your health care provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats and mice, Victoza® and medicines that work like Victoza® caused thyroid tumors, including thyroid cancer. It is not known if Victoza® will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.

Who should not use Victoza®?

Do not take Victoza® if:

  • you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
  • you are allergic to liraglutide or any of the ingredients in Victoza®.

What should I tell my health care provider before using Victoza®?

Before using Victoza®, tell your health care provider if you:

  • have or have had problems with your pancreas, kidneys, or liver.
  • have any other medical conditions or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food.
  • are pregnant or breastfeeding or plan to become pregnant or breastfeed.

Tell your health care provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and other medicines to treat diabetes, including insulin or sulfonylureas.

How should I use Victoza®?

  • Do not mix insulin and Victoza® together in the same injection.
  • You may give an injection of Victoza® and insulin in the same body area (such as your stomach area), but not right next to each other.
  • Do not share your Victoza® pen with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

What are the possible side effects of Victoza®?

Victoza® may cause serious side effects, including:

  • inflammation of your pancreas (pancreatitis). Stop using Victoza® and call your health care provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back.
  • low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Victoza® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery.
  • kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems to get worse.
  • serious allergic reactions. Stop using Victoza® and get medical help right away if you have any symptoms of a serious allergic reaction including itching, rash, or difficulty breathing.

The most common side effects of Victoza® may include headache, nausea, diarrhea, vomiting, and anti-liraglutide antibodies in your blood.

Please click here for Prescribing Information and Medication Guide .

Victoza® is a prescription medication.

Novo Nordisk provides patient assistance for those who qualify.
Please call 1-866-310-7549 to learn more about Novo Nordisk assistance programs.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.